Wednesday, January 5, 2011
Antioxidants: who needs 'em?
Let's start with the basics:
As your body works and metabolizes fuel (makes energy) it also produces reactive oxygen species, or ROS. Not to be confused with ROUS's (I don't even believe they exist). You may have also heard of them as Free Radicals. Your body makes them all the time during metabolism and when your metabolic needs increase when you are more active your ROS production increases too. Whatever the name is, most people agree that it is good to keep them in check. You see, generally your body oxidizes metabolites in order to break them down. Oxygen, as you may have inferred by the theme in naming here, is really good at oxidizing. The problem is when you have ROS attacking things in your body that they shouldn't attack...like your cells.
An antioxidant, then, is something that gets oxidized to stop your body from being damaged by getting oxidized. Some common simple antioxidants include Vitamin C and Vitamin E but there are many more that the body uses. In some ways it makes an antioxidant like a bodyguard taking a bullet for you.
The theory behind supplementing antioxidants is pretty sound, try and stop the dangerous ROS flying around by upping the number of body guards (antioxidants) in the system. But the proof is a bit lacking.
If we move on to the current evidence we see:
One study in Spain (M.E. Munoz et al. / Toxicology 278 (2010) 101–111) published recently, showed that there was a benefit for elderly exercisers whose body's natural defense mechanisms were a little worn out. But then again these participants were sedentary to begin with and the study was sponsored by the antioxidant drink that the participants were taking during the study.
Another study done by University of Wisconsin-Madison said the opposite, that perhaps helping your body deal with antioxidants stops your body from making other good adaptations to exercise. Most benefits from exercise actually come from stressing your body which includes the production of ROS. When you let your body recover from this stress, your body generally rebuilds itself as strong or stronger than before which is what allows for increased performance. Yet another more recent study in Germany echoed these findings by showing that exercisers who supplemented with antioxidants had less of an increase in insulin sensitivity than exercisers who did not take antioxidants. That means that antioxidant supplementation could actually decrease the effectiveness of exercise for managing Type 2 diabetes.
Finally, the idea of taking antioxidants as a daily supplement or in your multivitamin has lost a little bit of its credence since an article in JAMA came out that showed daily doses of antioxidant substances ranging from beta-carotene to Vitamin E may actually do more harm than good as a preventative measure.
The conclusion:
...a bit fuzzy. Antioxidants have reached craze status, this is confirmed by the fact that the word antioxidants has become a marketing catch phrase and is plastered all over everything from breakfast cereal to green tea. The science behind them is convincing, but as it turns out your body is pretty good at managing on its own.
Even in an event like an Ironman Triathlon, where there is a very significant increase in ROS production, healthy well trained athletes "experience no adverse health risks regarding oxidative stress" (Toxicology. 2010 Dec 5;278(2):211-6. Epub 2009 Sep 18). So for all of you endurance athletes out there who see Lance Armstrong drinking FRS in the commercials, don't be too quick to join the antioxidant party.
As with all fitness fads, it's best to give it a little time before following the crowd. That allows the scientists some time to straighten out the theory from the practice. And don't think the decision here is final. I'm sure it will be some time before this all really gets figured out and we stop going back and forth on what we think is best. Until then I'd say it's best to stick with what has lasted the test of time. Let your body do what it's been made to do by training regularly. It'll give you the jump on ROS you're looking for instead of dumping in extra unnecessary antioxidant supplements and relying on those to do the work for you. Then again, that's just my opinion and I'm no professional... at least not yet.
Friday, December 31, 2010
Making Plans
Wednesday, December 22, 2010
Simple Garlic Hummus
Monday, December 20, 2010
You need fat too!
You're body is made up of cells. A couple hundred years ago you might have looked at me and just said, "huh?" But thanks to the microscope and some advances in science (as well as public education) I feel pretty confident you can track with me here. Now where were we...ah yes, cells. You're body is made up of cells. Skin cells, stomach cells, hair cells, muscle cells, fat cells and more. Despite the fact that these cells all are part of different organs and systems, they have more in common than you may think. One of the things that all these cells have in common is their outer layer.
Cells have what is called a membrane which is composed of a lipid bilayer. What that basically means is that each cell is encased in a double layer of fat molecules. That's right fat molecules (aka lipids). And an important source for those cell walls is the fat that you eat. The fat you eat and cholesterol that you eat and that your body makes are mostly responsible for making the walls of your cells. The combination of those two components helps to determine how hard or soft those walls are. In the ideal world it would be the perfect combination of not too soft and not too hard, but every person is a little different based on their diet and their genetics.
This is part of the reason that trans fats are such a big deal. Initially when trans fats were invented we thought they were a great cheap solution to always needing plant or animal products, but as we quickly found out it's hard to beat nature at it's own game. By now it is impossible to go into a store without seeing bags of anything and everything labeled "0 Grams of Trans Fat" or "Trans Fat Free." That's because we learned that when trans fat gets included into our cell walls it tends to pack very tightly together. This means rigid cell walls (among other problems). Fats made by people and animals are almost exclusively cis-fats. While trans fats generally make straight linear molecules, cis-fats have some twists and bends in them. They create little extra spaces for molecules to move around and your cell membrane stays "softer" so to speak. Because of all of these problems trans fats are one item I would say are okay to put on the official "bad" list.
Another fat to avoid in excess is saturated fat. Saturated fats have similar properties in your cell to trans fats, but are naturally occuring in animal products and still not as bad as trans fats. This makes intuitive sense because we all are aware that eating a stick of butter or having bacon with every meal (both of which have a large amount of saturated fat) is not a good idea. Saturated fat, though, is not necessarily something to completely eliminate from your diet. For one, it would mean eating almost no animal products which is not a truly healthy or realistic option. In addition, your body can handle saturated fat and deal with it without too much difficulty, but just like any other nutrient if you eat too much of it you will not be happy with the outcome.
Now there are a couple of fats that are good for you. Namely unsaturated fats as well as omega-3 and omega-6 fatty acids. Unsaturated fats are found in nuts, seeds and other plant products and they are generally liquid at room temperature when they are isolated (as compared to saturated fats which are typically solid at room temperature-this is another good indicator of the quality of fat you are eating. Have the solids sparingly and enjoy the liquids). These unsaturated fats are the kinds that will leave your cells' walls soft and happy instead of rigid. Omega-3 and omega-6 fatty acids are important for multiple uses in the body, but they can't be made by humans, so they need to be eaten instead to be included in our bodies.
But now I've been babbling long enough, let's get to the payoff.
If you had to distill all of this information into a quick application it would be this. Don't avoid fat because you think "fat is bad." Fat has twice as many calories/gram as carbohydrate or protein so it's important to eat less of it if you want to avoid packing extra supplies of it on your body. However, it's not necessary to avoid it altogether and isn't good for you to do so either. Try enjoying some almonds instead of potato chips or using olive oil in place of butter. These are good ways to make sure that you get the fat you need without overdosing on the fat you don't need.
I know it's complicated, but you can do it. If you are just tuning in, check out more of this series on the three main nutrients under the Nutrition tags.
Wednesday, December 8, 2010
BMI is a baseline measure, but also a helpful one
Interestingly, a BMI that is too low is also bad for you (there is such a thing as being too skinny). But before you go pounding down twinkies to try and protect yourself from a low BMI, consider this. The increased risk to your health begins around a BMI of 18 which would be a 5' 6" tall person who weighed less than 118 lbs or a 6' tall person under 140 lbs.
If you're curious you can go to the NIH's BMI Caculator and see for yourself what your BMI is. If that's not enough for you, the next step to finding out more about what kind of shape you're in would be to find out your body composition or % body fat, but that's a conversation for another time.
Thursday, December 2, 2010
What's the big deal about protein?

"Remember, the healthiest diet is based on fruits, vegetables, whole grains and lean sources of protein — not rigid lists of 'good' and 'bad' foods. "
Thursday, November 25, 2010
Be Thankful
Friday, November 12, 2010
Carbohydrates are not evil
Wednesday, November 10, 2010
Portion size, why it is that a super-sized portion means a super-sized you.
So what?
Before we answer the "so what?" let's start by laying some baseline information. Calories are a measurement of energy. Calorie with a capital "C" is actually a kilocalorie, but we use Calories to talk about food because measuring in calories like physicists would give us giganticer numbers than we want to deal with. Your body needs a certain number of calories per day which it gets from food. Food is your fuel. There are three main pathways that those fuels take when you eat them. They get used for 1)energy now, 2)they get stored as energy specifically for muscle in glycogen or 3) they get stored away as fat.
Now let's answer the "so what?" question.
If I only need around 2000 calories per day to do everything that my body needs to do what does it do with the extra? It stores it! Let me introduce you to your friend, the liver. The liver organizes most all of this fuel. It's first job is to maintain your blood sugar. If you don't have enough glucose in your blood the liver will move glucose into your blood. If you have too much glucose in your blood, the liver will take it out and send it where it can be stored. Pretty handy organ to have, eh? The liver also does a lot to direct the storage of extra fuel as both glycogen and fat. But here's the deal, you're body can only store so much glycogen before it's full. Fat cells on the other hand just keep getting bigger and bigger the more you stuff in them. It's not such a bad system when you don't know when your next meal will be, but living a developed nation we can usually count on eating every day. Which means that if you don't want to store food as fat you need to control your caloric intake.
There are two really important ways to do this. First, keeping an eye on your daily caloric intake vs. output. If you are using 2600 calories a day and eating 3000 you are going to have 400 extra calories a day that the body wants to hang on to, which means more fat. This explains the well known idea that if calories in > calories out you will gain weight.
Let's get more specific though and talk about how much you eat at one time. Would you believe me if I told you that eating 5 times a day is better for your body composition than eating 3 times a day? What if I explained that you would be eating the same number of calories, but in smaller portions spread throughout the day? Think about the liver's priorities..1)blood sugar, 2) glycogen, 3) fat. All right, so now imagine you ate 2500 calories in 5 portions. That means that you would eat around 500 calories each time you ate. Not too bad. That's a big PB&J sandwich. But it also means that your portions are small enough that you are primarily addressing liver priorities #1 and #2. Once the food is used to balance your blood sugar and fill up your glycogen tank there may not be any left for your fat stores. Now that's pretty cool!
Try it and see how it works for you. The worst part is the inconvenience of eating outside of the normal Breakfast-Lunch-Dinner window. However, eating small portions several times a day, will help your body to store less fat and use more of the energy it is consuming when it enters the body.
Wednesday, November 3, 2010
Food is Fuel
The difference is that our bodies also have batteries. The problem being that the batteries for our body tend to come in the form of love-handles rather than the nice copper tops. That's right, fat is the human battery. It's the primary way that we store energy for using later and it's pretty stinking good at storing a lot of energy (we can talk more later about how fat really isn't a bad thing unless you have too much of it).
Food is fuel. Sounds great, but what does it really mean. It means that what you eat lets your body do what it needs to do. There are three main nutrients that give energy to your body, protein, fat and carbohydrate. There is potential energy stored up in all of the chemical bonds that exist in the foods you eat. When you eat, your body breaks those bonds and transfers the energy in them to make other molecules your body can use, primarily ATP. Don't worry that's about the end of the sciencey discussion for now. The bottom line being that if you don't eat, you don't get the energy you need to do the things you like to do like running, biking, swimming etc.
There are three main plans that your body has for the fuel you put into it: 1) turn it into glucose right away to maintain your blood sugar levels and feed your brain, 2) store some energy in small energy stores for muscles called glycogen so that your muscles have the immediate energy they need to do things like walk, jump, sit, stand, etc. and 3) store whatever is left as fat.
Your body's goal is always to use the fuel you give it, even if you give it too much. Now the trick is finding out how much fuel you need and to give yourself the right amount. A good place to start is by doing a simple calculation of a basal metabolic rate. There are lots of calculators on the internet that you can find which will help you do this. The basal metabolic rate really is just a starting point though, because this is the absolute minimum number of calories you need in a day. Which means that even someone who has a sedentary job will burn more calories than their BMR...albeit not a lot more. The more active you are the more calories you burn because your muscles are using more fuel. Makes enough sense, right? If you drove your car 100 miles a day it would need more gas than if you drove it 10 miles a day. It's the same idea. Some calculators will try to compensate for this by giving you an opportunity to estimate activity level, like this one I found or the Livestrong.com calorie calculator. These are only estimates, but they work fairly well.
Not all fuels are created equally, either because you are never getting just one nutrient from what you eat. This is a good thing too. Interestingly enough it is often found that natural whole foods frequently have a combination of nutrients and vitamins that complement each other in such a way to benefit your body. For instance, eating an orange or a bell pepper is a more efficient way for your body to obtain vitamin C than taking supplements...but now we're getting into vitamins and other add ons. They aren't really fuel, but they help your body do what it needs to do with the fuel. We'll leave that for later.
Ultimately you need to choose your fuel carefully. Most people would be quick to agree that eating all fat is no good, but eating all protein is also no good. Foods need to be balanced between nutrients (fat, protein and carbohydrate) and they need to be enough to meet your needs. A caloric deficit--which is what you usually aim for whenever you go on a diet--will make your body lose weight, but it will also stress your body. Remembering that food is fuel will help you realize that when you eat you should be considering the amount of energy you have used or will need to use. The key being balance and establishing a beneficial average quantity.
Until next time, fuel up!
Thursday, October 28, 2010
An exercise in discipline
Wednesday, October 27, 2010
What you eat and what your body does with it...
Tuesday, September 7, 2010
我喜歡喝茶
Wednesday, August 11, 2010
The new kid
Up until now, every class I've been in has been populated primarily with people more like me. We've all lived closer together (except college maybe), we were all closer in age and generally closer in background. Here we all have some things in common. We all want to be doctors, we all went to college (at least I think so), we all eat and breathe and sleep and study... A LOT. And we're all bored with orientation and ready to hit the books, sort of, I guess. Regardless of what we have in common it all feels a bit different than anything before this. Which is probably a good thing. I mean, no one wants medical school to feel like kindergarten, right? Just imagine what our health care system would look like then. Oof.
Even though it's orientation, we still get a bit of a feel for what it will be like time wise. It's going to be really hard to do a lot more than go to school, eat and sleep, but it's definitely doable. The prospect of minimal free time makes me value my summer that much more. It was awesome. I'm going to miss riding my bike 8+ hours a week.
However, in an effort to stay sane and not squishy I have resolved to take steps to be involved in "non-studious" activities and "good lifekeeping" habits.
1. Eat good food and at home whenever possible. (note: good food)

Tuesday, August 10, 2010
Eat at Home
Monday, August 9, 2010
Yummm... Smoothies
Thursday, July 15, 2010
Sometimes it's hard to eat enough.
Some of the riders at the Tour share telemetric information with the media just for fun. Jens Voigt is frequently one of those riders. He often shares his real time heart rate, power output and speed so that they can show the data while airing the Tour. It's cool, but humbling when you see that he's just cruising along around 30 MPH with a heart rate in the low 130's. In addition, two days ago, Jens was working like a madman to get Andy Schleck in Yellow and reported to journalists that he burned 6000 calories during his ride up and over the Col de la Madeleine. That's only in one day. Doing work like that, riders sometimes have to eat as much as 9000 calories per day. Yikes!
I found this article last year by Joel Stein about trying to eat that much. Here it is for your reading pleasure. In the meantime, while I prepare for my day in the mountains tomorrow I think I'm going to have a snack...
"What's Tougher, Riding or Eating" by Joel Stein
As much as I'd like to experience the Tour de France, I don't enjoy being on a bike for more than 90 minutes or going uphill. So after years of longing as an obsessive fan, I came up with another, more American way to experience the thrill of the Tour.
I would eat everything the riders do.
After all, as impressive as riding 125 miles up the Pyrenees in five hours is, eating 9,000 calories in a day is far better. And it's a goal that, through training, determination and possibly vomiting, I figured I could attain.
So I called Team Columbia and asked for its menu from one of the hardest days of the 2008 Tour, which included the insane climbs up Col du Tourmalet and Hautacam. Looking at the six meals -- the caloric equivalent of nearly five days of food for a normal adult male -- was the gastronomical equivalent of staring up at a cloud-covered mountain as you approached it (or what I assume it would feel like to stare up at a cloud-covered mountain as you approached it). Apparently these guys needed so many calories that day that Team Columbia's professional nutritionist required them to drink two Coca-Colas. I kept rechecking the list to make sure there were no Twinkies on it.
I soon decided that if I were to be true to myself and my American heritage, I'd have to attempt this feat while sitting on my couch, watching live cycling coverage. It would be all calories in and no calories out -- at least not through sweating. (Unless I was sweating over a toilet bowl.)
Also, in camaraderie with the Tour, which is trying to eliminate performance-enhancing drugs, I vowed not to smoke any marijuana.
TEAM COLUMBIA MENU
STAGE 17, TOUR DE FRANCE 2008
Breakfast
• Banana (1)
• Muesli (150 gr)
• Pasta (150 gr -- weight is non-cooked)
• Croissant with chocolate (1)
• Coffee (250 ml)
• Soy milk (300 gr)
• Mixed fruits (200 gr)
• Orange juice (300 ml)
Pre-race
• Pasta (150 gr)
• Water (500 ml)
Race
• PowerBar (4)
• Fruit cake (100 gr)
• PowerBar carbo drink (4000 ml)
• PowerBar energy gels (4)
• Coca-Cola (400 ml)
• Turkey sandwich (2)
• Water (1000 ml)
Post-race
• Recovery drink (500 ml)
• Turkey sandwich (1)
• PowerBar (1)
• Coca-Cola (330 ml)
• Fruit cake (100 gr)
• Water (400 ml)
Dinner
• Mixed vegetables (200 gr)
• Pasta (200 gr)
• Chicken breast (250 gr)
• Sauce (100 gr)
• Plain yogurt (350 gr)
• Mixed fruits (150 gr)
• Water (800 ml)
Pre-sleep
• Gum/sweets (100 gr)
• Chocolate (25 gr)
• Water (500 ml)
Before any record-shattering athletic feat is attempted, it's always best to check with a medical professional. My longtime doctor, Robert Samuelson, gave it some thought and concluded, "It would not hurt you at all" and "You'll gain weight." He also said it wouldn't be much different than eating a couple of Big Macs in a day. Let me just say that while Dr. Samuelson is a great doctor and a smart guy, he clearly knows very little about the McDonald's menu. I would have to eat 17 Big Macs to equal the Team Columbia daily caloric intake.
On the morning of my attempt, I woke up extra early just to start eating, which felt rather weird. Unfortunately, it took me almost an hour to prepare breakfast, so I didn't actually start consuming food until about 9 a.m., putting me behind schedule from the start. In front of me, I saw what looked like one of those expensive hotel Sunday brunch buffets that includes breakfast, lunch, dessert and a meal not yet invented.
I enjoyed the fruit, and a half-pound of pasta with olive oil is never a bad thing. But I do not know what the Swiss do all day that requires muesli to be the densest food ever made in non-bar form. The only way I could get through my bowl of it was to revive myself occasionally with little bites of the chocolate croissant.
I felt so full afterward, I broke my own rule and went out for a walk, which turned into a hike. Even Tour riders don't cheat during breakfast.
Before the race starts, there is another meal -- for which I was not yet hungry at all, having eaten an hour ealier. I plowed through the other half of the box of pasta and downed it all with two pitchers of bright pink PowerBar carbo drink, which made me imagine a summer camp for kids who are too skinny. But halfway through I broke down, sweating, with stomach pains. I have no idea how you can eat this much and then feel like getting on a bike. Or how you can eat this much when you're nervous about racing. Or how you can eat this much if you're an adult elephant.
As I watched the race on TV, I alternated between two turkey sandwiches, four peanut butter PowerBars, four PowerBar energy gels and two Cokes. I looked at the riders' grimacing faces and knew I was suffering more. As I sipped my second Coke, my eyes started watering and I desperately wanted to barf. But then, thankfully, the race ended. I was a whole lot of carbo drink, one PowerBar, three gels and a piece of fruit cake behind schedule. Cadel Evans, who'd won the day's race, was smiling and talking on TV, not enduring anything close to what I was. I kept wondering what would happen if those two women on the podium with him tried to kiss me. It could be ugly.
An hour later, as I sat down for my postrace meal, I'd recovered impressively -- I downed another turkey sandwich, my fourth PowerBar of the day and another Coke. The PowerBar made my jaw ache, but mostly, I was just dealing with the clichéd self-recriminations of an athlete after a loss. I could have dealt with the jaw fatigue and had another PowerBar, but I held off. I vowed to make up for it later that night.
I had to head out to a movie screening in the early evening, but I took my predinner snacks with me. I was gnawing on a giant piece of fruit cake 30 minutes into the film when, suddenly, my face turned red and I felt feverish, as if that last little bit of food had activated all the other food still inside me. I made it about 10 feet out of the theater before I saw that I was following none other than Larry King into the men's room. And I immediately felt very, very bad for him.
I'll spare you the gory details on that portion of the evening. Suffice it to say I went to the bathroom six times that day. I'm not a scientist, and this was not a real experiment, but I learned at least one thing from all of this: You give the human body enough calories in a short enough period of time, and it doesn't have time to turn it all into fat. One way or another, those calories get turned to waste.
I also learned I'm an idiot who does idiotic things.
At 11 p.m., with just an hour to go, I stared at the uncooked chicken breast, vegetables, fruit, yogurt, chocolate and (unbelievably) more pasta I had left to tackle -- and I dropped out. I fell short by more than 2,000 calories. And I marveled, more than ever, about how different I am from professional athletes.
I guess I will never know what it's like, on any level, to be a Tour de France rider. Which fills me with the kind of shame only known by people who fail in an attempt to do something stupid that no one cares about.
The shame of Robbie Knievel.
The philanthropist and humanitarian Joel Stein is based in Los Angeles and a Time magazine columnist.